N-Arachidonylglycine,N-(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)glycine

N-Arachidonylglycine (NAGly) is a carboxylic analog of the endocannabinoid anandamide. Since it was first synthesized in 1996, NAGly has been a primary focus of the relatively contemporary field of lipidomics due to its wide range of signaling targets in the brain, the immune system and throughout various other bodily systems. In combination with 2‐arachidonoyl glycerol (2‐AG), NAGly has enabled the identification of a family of lipids often referred to as endocannabinoids. Recently, NAGly has been found to bind to G-protein coupled receptor 18 (GPR18), the putative abnormal cannabidiol receptor. NaGly is found throughout the body and research on its explicit functions is on going.