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Picture of N-(4-Hydroxyphenyl)Thiourea

N-(4-Hydroxyphenyl)Thiourea

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Origin: China

Cas No: 1520-27-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 1520-27-0 Formula: C7H8N2OS Molecular Weight: 168.21600

    Description

    1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.

    Basic Info

    Chemical Name N-(4-Hydroxyphenyl)Thiourea
    Synonyms

    (4-hydroxyphenyl)thiourea;
    N-(4-Hydroxyphenyl)thiourea;

    CAS No. 1520-27-0
    Molecular Formula C7H8N2OS
    Molecular Weight 168.21600
    PSA 90.37000
    LogP 1.82100

    Properties

    Density 1.45g/cm3
    Boiling Point 341.5ºC at 760mmHg
    Melting Point 214ºC
    Flash Point 160.3ºC
    Refractive Index 1.777
    Vapor Pressure 4.05E-05mmHg at 25°C

    Safety Info

    RTECS YT5250000
    Safety Statements S22-S36/37
    HS Code 2930909090
    Risk Statements R22

    Synthesis Route

    Benzamide, N-[[ (4-hydroxyphenyl)amino]thioxomethyl]-N-(4-Hydroxyphenyl)Thiourea
    4-HYDROXYPHENYLISOTHIOCYANATEN-(4-Hydroxyphenyl)Thiourea
    N,N-diethylethanamine,(4-hydroxyphenyl)carbamodithioic acidN-(4-Hydroxyphenyl)Thiourea

    Precursor

    ammonium thiocyanate
    4-Aminophenol Hydrochloride
    4-HYDROXYPHENYLISOTHIOCYANATE
    Benzamide, N-[[ (4-hydroxyphenyl)amino]thioxomethyl]-

    Downstream Product

    2-Amino-benzothiazol-6-ol
    2-methylsulfanyl-3-[4-[3-(4-phenylpiperazin-1-yl)propoxy]phenyl]pyrimidin-4-one

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