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Picture of N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

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Origin: China

Cas No: 138-56-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 138-56-7 Formula: C21H28N2O5 Molecular Weight: 388.45700

    Description

    Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting. It is often prescribed for patients with gastroenteritis, medication-induced nausea, and other illnesses. Trimethobenzamide is generally considered the most potent antiemetic that does not have effects on the serotonergic, dopaminergic, or histaminergic systems, so it has a lower likelihood of causing undesired side effects. In the United States, it requires a prescription.

    Basic Info

    Chemical Name N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide
    Synonyms

    Tebamide;
    Trimethobenzamid;
    Trimethobenzamidum;
    Trimazide;
    Benzacot;
    trimethobenzamide;
    Tribenzagan;
    Tigan;
    Stemetic;
    Trimetobenzamida;

    CAS No. 138-56-7
    Molecular Formula C21H28N2O5
    Molecular Weight 388.45700
    PSA 69.26000
    LogP 2.97370

    Properties

    Density 1.131 g/cm3
    Boiling Point 506.9ºC at 760 mmHg
    Flash Point 260.4ºC
    Vapor Pressure 2.13E-10mmHg at 25°C

    Safety Info

    HS Code 2924299090

    Synthesis Route

    2-[4-(aminomethyl)phenoxy]-N,N-dimethylethanamine+3,4,5-Trimethoxybenzoyl chlorideN-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide
    4-[2-(DIMETHYLAMINO)ETHOXY]BENZALDEHYDEN-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide
    4-hydroxybenzaldehydeN-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

    Precursor

    3,4,5-Trimethoxybenzoyl chloride
    4-[2-(DIMETHYLAMINO)ETHOXY]BENZALDEHYDE
    2-[4-(aminomethyl)phenoxy]-N,N-dimethylethanamine
    3,4,5-trimethoxybenzoic acid

    Downstream Product

    N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide,hydrochloride

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