Home > Organosulfur Compounds> N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide

N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide

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Origin: China

Cas No: 186497-07-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 186497-07-4 Formula: C19H16N6O4S Molecular Weight: 424.43300

Description

Zibotentan (INN) (earlier code name ZD4054) is an anti-cancer candidate. It is an endothelin receptor antagonist.
It failed a phase III clinical trial for prostate cancer but other trials are planned. Tolerability of zibotentan plus docetaxel has been evaluated.

Basic Info

Chemical Name	N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide
Synonyms	Zd 4054; ZD4054,Zibotentan; Zibotentan;
CAS No.	186497-07-4
Molecular Formula	C19H16N6O4S
Molecular Weight	424.43300
PSA	141.37000
LogP	3.86020

Properties

Density	1.423 g/cm3
Boiling Point	636.996ºC at 760 mmHg
Flash Point	339.043ºC

Safety Info

Hazard Declaration	H302
Symbol	GHS07
Signal Word	Warning
Caution Statement	P301 + P312 + P330

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