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Home > Organosulfur Compounds> MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid
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MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid

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Origin: China

Cas No: 115104-28-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 115104-28-4 Formula: C26H27ClN2O3S2 Molecular Weight: 515.08700

    Description

    A receptor antagonist for the treatment of respiratory diseases. Cysteinyl leukotriene receptor antagonist MK-571 alters bronchoalveolar lavage fluid proteome in asthma.

    Basic Info

    Chemical Name MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid
    Synonyms

    MK-571 SODIUM SALT;
    MK-571 NA;
    MK-571,NA SALT;

    CAS No. 115104-28-4
    Molecular Formula C26H27ClN2O3S2
    Molecular Weight 515.08700
    PSA 121.10000
    LogP 6.47660

    Properties

    Density 1.327g/cm3
    Boiling Point 712.3ºC at 760mmHg
    Flash Point 384.6ºC
    Vapor Pressure 2.72E-21mmHg at 25°C

    Synthesis Route

    (E)-methyl 3-(((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoate→MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid
    7-Chloro-2-methylquinoline→MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid
    m-Phthalaldehyde→MK 571,3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoicacid

    Precursor

    2-(BROMOMETHYL)-7-CHLOROQUINOLINE
    m-Phthalaldehyde
    (E)-methyl 3-(((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoate
    3-(HYDROXYMETHYL)BENZALDEHYDE

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