Welcome to GlobalChemMall

ALL CATEGORIES
Categories
Picture of metronidazole

metronidazole

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 443-48-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

  • Products Specification
  • Product Description
  • Product Introduction:
    Common name: Metronidazole
    Chemical Name: 2 - methyl -5-- nitroimidazole-1-alcohol
    Chemical Formula: C6H9N3O3
    Molecular Weight: 171.15
    CAS number: 443-48-1
    Property: White or yellowish crystal or crystalline powder; have slightly smelly, bitter and slightly salty .. This product is slightly soluble in ethanol, in water or chloroform, slightly soluble, very slightly soluble in ether.
    Shelf life and storage: 4year (dry, avoid light and sealed)
    Use:
    Application:
    1. Metronidazole slice
    2. Metronidazole Vaginal Effervescent Tablets
    3. Metronidazole Injection
    5. Metronidazole Capsule
    6. Metronidazole Glucose Injection
    Package: 25KG/paper barrel or packed according to the requirements of customers.
    Indications: for the treatment of intestinal and parenteral amebiasis (such as amoebic liver abscess, pleural amebiasis, etc.). but also for the treatment of vaginal trichomoniasis, coccidiosis pouch and cutaneous leishmaniasis, Guinea worm infection. is still widely used in the treatment of anaerobic infections.

  •  

    Property

    CAS No.: 443-48-1 Formula: C6H9N3O3 Molecular Weight: 171.15400
     

    Description

    Metronidazole (MNZ), marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. It is the drug of choice for a first episode of mild-to-moderate Clostridium difficile colitis. Metronidazole is available by mouth, as a cream, and intravenously.
    Common side effects include nausea, a metallic taste, loss of appetite, and headaches. Occasionally seizures or allergies to the medication may occur. Metronidazole should not be used in early pregnancy but appears to be safe later in pregnancy. It should not be used when breastfeeding.
    Metronidazole began to be commercially used in 1960 in France. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available in most areas of the world. The pills are not very expensive being between 0.01 and 0.10 USD each. In the United States it is about 26 USD for ten days of treatment.
     

    Basic Info

    Chemical Name metronidazole
    Synonyms

    2-methyl-5-nitroimidazole-1-ethanol;
    Metronidazole;
    1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;
    CLONT;
    Klion;
    Cont;
    Nalox;
    Elyzol;
    Flagil;
    2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol;
    Bexon;
    Klont;
    2-(2-Methyl-5-nitro-1-imidazolyl)ethanol;
    Eumin;
    Nida;

    CAS No. 443-48-1
    Molecular Formula C6H9N3O3
    Molecular Weight 171.15400
    PSA 83.87000
    LogP 0.61520
     

    Properties

    Appearance & Physical State White to slightly yellow crystalline powder.
    Density 1.45 g/cm3
    Boiling Point 405.4ºC at 760 mmHg
    Melting Point 159-163ºC
    Flash Point 199ºC
    Refractive Index 1.612
    Stability Stable. Incompatible with strong oxidizing agents.
    Storage Condition 2-8ºC
    Vapor Pressure 2.67E-07mmHg at 25°C
     

    Safety Info

    RTECS XH8425000
    Safety Statements S36/37-S45-S53
    HS Code 2933990090
    WGK Germany 3
    Risk Statements R40; R46; R45
    Hazard Codes T
    Hazard Declaration H351
    Caution Statement P281
    Signal Word Warning
    Symbol GHS08
     

    Synthesis Route

    metronidazole benzoate+benzoic acid→metronidazole
    oxirane+2-Methyl-4(5)-nitroimidazole→metronidazole
    2-(2-methyl-5-nitroimidazol-1-yl)ethyl dihydrogen phosphate→metronidazole
     

    GC Analysis

    Column typeActive phaseTemperature (°C)Retention Index (I)Temperature Control Method
    Packed SE-30 180. 1618. isothermal
    Packed SE-30 - 1590. temperature ramp
    Other Methyl Silicone - 1592. custom temperature program
     

    Precursor

    oxirane
    2-(2-methyl-5-nitroimidazol-1-yl)ethyl dihydrogen phosphate
    metronidazole benzoate
    2-Methyl-4(5)-nitroimidazole
     

    Downstream Product

    2-(2-methyl-5-nitroimidazol-1-yl)ethyl 3,4,5-triacetyloxybenzoate
    Ethanolammonium nitrite
    2-(2-methyl-5-nitroimidazol-1-yl)ethyl 3,4,5-trimethoxybenzoate
    Glyoxal bishydrazone

Hot tags: metronidazole, China, manufacturers, suppliers, factory, wholesale, low price, high quality