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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> Methylprednisolone sodium hemisuccinate
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Methylprednisolone sodium hemisuccinate

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Origin: China

Cas No: 2921-57-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 2921-57-5 Formula: C26H34O8 Molecular Weight: 474.54300

    Description

    6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone, a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.

    Basic Info

    Chemical Name Methylprednisolone sodium hemisuccinate
    Synonyms

    Urbason-Soluble;
    methylprednisolone 21-hemisuccinate;
    6-methylprednisolone-21-hemisuccinate;
    methylprednisolone hemisuccinate esters;
    Methylprednisolone hydrogen succinate;
    4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;
    METHYLPREDNISOLONE HEMISUCCINATE;
    Solumedrol;
    EINECS 220-863-9;
    UNII-5GMR90S4KN;
    METHYLPREDNISOLONE SODIUM SUCCINATE;
    methylprednisolone succinate;

    CAS No. 2921-57-5
    Molecular Formula C26H34O8
    Molecular Weight 474.54300
    PSA 138.20000
    LogP 2.21930

    Properties

    Density 1.33g/cm3
    Boiling Point 689.6ºC at 760mmHg
    Flash Point 230.7ºC
    Refractive Index 1.593
    Vapor Pressure 5.28E-22mmHg at 25°C

    Safety Info

    HS Code 2942000000

    Synthesis Route

    4-[[(6S,8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid→Meprednisone+Methylprednisolone sodium hemisuccinate
    4-[[(6S,8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid→Methylprednisolone sodium hemisuccinate

    Precursor

    4-[[(6S,8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid

    Downstream Product

    Meprednisone
    4-[[(6S,8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid

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