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Picture of 2-Methyl-4-Isothiazoline-3-one (MIT)

2-Methyl-4-Isothiazoline-3-one (MIT)

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Origin: China

Cas No: 2682-20-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description

  • 2-Methyl-4-Isothiazoline-3-one (MIT)

    CAS No. :  2682-20-4

    Molecular Formula:   C4H5NOS

    Molecular weight:  115.15 

    Structural Formula:

    Synonyms:

    2-Methyl-2,3-dihydroisothiazol-3-one; 2-Methylisothiazol-3-one; Isothiazolone, 2-methyl-; Methyl-3(2H)-isothiazolone; Skycide 100; 2-Methyl-3-isothiazolone; 2-Methyl-Isothiazolin-3-one; 1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA; 2-METHYL-3(2H)-ISOTHIAZOLONE; N-METHYL-3-OXODIHYDRO ISOTHIAZOLE; 2-methyl-3(2h)-isothiazolon; Isothiazolone,2-methyl-; Methylisothiazolinone; 2-Methyl-4-Isothiazoline-3-Ketone; 2-Methyl-4-Isothiazolin-3-Ketone; MIT ISOTHIAZOLONE

     

    MIT-50

     

    Item

    Description

    Appearance

    Colorless or yellow transparent liquid

    Content of Active Substance (%)

    ≥50

    pH value

    5.0～7.0

    Density (g/ml)

    ≥1.10

    Packaging    
    1,000 kg per IBC drum, 200 kg per drum.
    Storage and Transportation 
    To be stored at room temperature in a dark place; with a shelf time of one year

     

    MIT-20

     

    Item

    Description

    Appearance

    Yellowish transparent liquid

    Content of Active Substance (%)

    ≥20

    pH value

    4.0～6.0

    Density (g/ml)

    ≥1.02

     

    Packaging    
    1,000 kg per IBC drum, 200 kg per drum.
    Storage and Transportation  

    To be stored at room temperature in a dark place; with a shelf time of one year

     

    MIT-10

     

    Item

    Description

    Appearance

    Yellowish transparent liquid

    Content of Active Substance (%)

    ≥10

    pH value

    4.0～7.0

    Density (g/ml)

    ≥1.02

    Packaging    
    1,000 kg per IBC drum, 200 kg per drum.
    Storage and Transportation 
    To be stored at room temperature in a dark place; with a shelf time of one year

     

    Performance characteristics
    1. Serve as a broad-spectrum, long-lasting biocide to kill many bacteria, fungi and yeasts; applicable in solutions of the pH value in the range of 2.0-12.0.
    2. Miscible with water and alcohol; can be added at any production step; its low toxicity and an appropriate concentration of using will cause no harm.
    3. Cause no residue after discharge, and no accumulation of pollution to environment; not combustible and easy to transport and use.
    4. Good compatibility with all kinds of emulsifiers, surfactants and protein.
    5. Colorless and odorless; can be used in cosmetics; contain no formaldehyde and VOC.

    Usage andCautions 
    1. For use in cosmetics, body care products, and other daily chemicals, the concentration of using is in the range of 0.05-0.40% (w/w) depending on the storage environment and whether the product is susceptible to the destroy of microorganisms. The specific formula and instructions for the concentration of using will be based on the company's microbial technology division
    2. It can be added at any production step; but it's suggested to be added at the final step at less than 50 ℃; avoid adding at a temperature of higher than 50 ℃.
    3. Wear protective clothing, rubber gloves and goggles and masks, avoid contact with skin, eyes and mucous membranes.

  •  

    Property

    CAS No.: 2682-20-4 Formula: C4H5NOS Molecular Weight: 115.15400
     

    Description

    Methylisothiazolinone, MIT, or MI, (sometimes erroneously called methylisothiazoline), is a powerful synthetic biocide and preservative within the group of isothiazolinones, which is used in numerous personal care products and a wide range of industrial applications.
    It is a cytotoxin that may affect different types of cells. Its use for a wide range of personal products for humans, such as cosmetics, lotions, moisturizers, sanitary wipes, shampoos, and sunscreens, more than doubled during the first decade of the twenty-first century and is proving to be a concern because of sensitization and allergic reactions as well as cell and nerve damage.
    Industrial manufacturing and distribution of the biocide has resulted in more severe health hazards to the humans involved in the handling of large concentrated quantities of the biocide.
    Industrial applications also are quite wide ranging, from preservative and sanitizing uses to antimicrobial agents, energy production, metalworking fluids, mining, paint manufacturing, and paper manufacturing, many of which increase potential exposure to it by humans as well as organisms, both terrestrial and marine. Industrial applications in marine environments are proving to be toxic to marine life, for instance, when the effect of its now almost-universal use in boat hull paint was examined.
     

    Basic Info

    Chemical Name Methylisothiazolinone
    Synonyms

    2-methyl-2H-isothiazol-3-one;
    2-Methyl-4-Isothiazolin-3-one;
    METHYLISOTHIAZOLIN;
    2-Methyl-3(2H)-isothiazolone;
    2-METHYLISOTHIAZOLINONE;
    METHYLISOTHIAZOLINE;
    2-methylisothiazolone;
    2-methylisothiazolin-3-one;
    METHYLISOTHIAZDINONE;
    Skycide 100;
    METHYLISOTHIAZOLONE;
    KATHONCG;
    methylisothiazolin-3-one;
    N-methyl-isothiazole-HCl;
    2-Methylisothiazol-3(2H)-one;
    Isothiazolone,2-methyl;
    MIT;
    2-Methyl-4-isothiazoline-3-one;
    2-methyl-3-isothiazolone;

    CAS No. 2682-20-4
    Molecular Formula C4H5NOS
    Molecular Weight 115.15400
    PSA 50.24000
    LogP 0.44680
     

    Properties

    Appearance & Physical State White to yellow powder
    Density 1.25 (14% aq.)
    Boiling Point 182.8ºC at 760 mmHg
    Melting Point 254-256ºC
    Flash Point 64.3ºC
    Vapor Pressure <0.1 mm Hg ( 25 °C)
     

    Safety Info

    RTECS FE1250000
    Hazard Class 8
    Safety Statements S24-S26-S36/37/39-S60-S61
    HS Code 2934100090
    WGK Germany 2
    Packing Group III
    RIDADR UN 3077 9/PG 3
    Risk Statements R20/21/22; R34; R43; R50
    Hazard Codes C
    Symbol GHS05, GHS06, GHS09
    Caution Statement P261; P273; P280; P305 + P351 + P338; P310
    Hazard Declaration H302; H314; H317; H331; H335; H400
    Signal Word Danger
     

    Synthesis Route

    N,N'-Dimethyl-3,3'-dithiodipropionamide→chloromethylisothiazolinone+4,5-dichloro-2-methyl-1,2-thiazol-3-one
    N,N'-Dimethyl-3,3'-dithiodipropionamide→chloromethylisothiazolinone+Methylisothiazolinone
    5-(4-methoxybenzoyl)-2-methylisothiazol-3(2H)-one→Methylisothiazolinone
     

    GC Analysis

    Column typeActive phaseTemperature (°C)Retention Index (I)Temperature Control Method
    Capillary HP-5 MS - 1431. custom temperature program
     

    Precursor


    N,N'-Dimethyl-3,3'-dithiodipropionamide
    5-(4-methoxybenzoyl)-2-methylisothiazol-3(2H)-one
    2-methyl-1,2-thiazolidin-3-one
     

    Downstream Product

    4,5-dichloro-2-methyl-1,2-thiazol-3-one

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