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Methyl 3-(4-hydroxyphenyl)propionate

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Origin: China

Cas No: 5597-50-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 5597-50-2 Formula: C10H12O3 Molecular Weight: 180.20000

Description

3-(4-Hydroxyphenyl)propionic Acid Methyl Ester is a useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents.

Basic Info

Chemical Name	Methyl 3-(4-hydroxyphenyl)propionate
Synonyms	METHYL P-HYDROXYHYDROCINNAMATE; Methyl 4-hydroxyphenylpropionate; p-Dihydrocoumaric acid methyl ester; Methyl p-hydroxyphenylpropionate; Methyl 4-hydroxyhydrocinnamate;
CAS No.	5597-50-2
Molecular Formula	C10H12O3
Molecular Weight	180.20000
PSA	46.53000
LogP	1.49780

Properties

Appearance & Physical State	white to off-white crystal
Density	1.146g/cm3
Boiling Point	108ºC (11 mmHg)
Melting Point	37-41ºC
Flash Point	124ºC
Refractive Index	1.635
Storage Condition	2-8ºC

Safety Info

Safety Statements	S26-S37/39
HS Code	2918290000
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Methanol+phloretic acid→Methyl 3-(4-hydroxyphenyl)propionate
phloretic acid+iodomethane→Methyl 3-(4-hydroxyphenyl)propionate
Methyl 4-hydroxycinnamate→Methyl 3-(4-hydroxyphenyl)propionate

Precursor

phloretic acid
iodomethane
Methyl 4-hydroxycinnamate
4-coumaric acid

Downstream Product

phloretic acid
3-(4-phenylmethoxyphenyl)propanoic acid
3-(4-hydroxyphenyl)propanal
3-(4-methoxyphenyl)propanal

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