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Picture of Methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate

Methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate

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Origin: China

Cas No: 149968-11-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 149968-11-6 Formula: C28H22ClNO3 Molecular Weight: 455.93200

    Description

    An intermediate in the synthesis of Montelukast.

    Basic Info

    Chemical Name Methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate
    Synonyms

    2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester;
    2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester;
    (E)-2-[3-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-oxopropyl]-1-(methoxy-carbonyl)benzene;
    methyl (E)-2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate;
    METHYL 2-(3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-OXOPROPYL)BENZOATE;
    (E)-2-(3-(3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl)-3-oxo-propyl)-benzoic acid methyl ester;
    2-(3-(2-(7-chloro-2-quinolinyl)-ethenyl-phenyl)-3-oxo-propyl)-1-methoxycarbonylbenzene;
    methyl (E)-2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate;
    2-(3-(3-((E)-2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-3-oxopropyl)benzoic acid methyl ester;
    (E)-2-[3-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester;

    CAS No. 149968-11-6
    Molecular Formula C28H22ClNO3
    Molecular Weight 455.93200
    PSA 56.26000
    LogP 6.66070

    Properties

    Density 1.271
    Boiling Point 659.723ºC at 760 mmHg

    Synthesis Route

    Methyl 2-iodobenzoate+1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]prop-2-en-1-olMethyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate
    methyl 2-[2-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]benzoyl]-3-methoxy-3-oxopropyl]benzoate(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid+Methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate
    7-chloro-2-ethenylquinoline+2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid methyl esterMethyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-oxopropyl)benzoate

    Precursor

    2-[3-(3-bromo-phenyl)-3-oxo-propyl]-benzoic acid methyl ester
    methyl 2-[2-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]benzoyl]-3-methoxy-3-oxopropyl]benzoate
    Methyl 2-iodobenzoate
    7-chloro-2-ethenylquinoline

    Downstream Product

    methyl 2-[(3R)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxypropyl]benzoate
    (1S)-1-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}-3-[2-(2-hyd roxy-2-propanyl)phenyl]-1-propanol
    METHYL 2-[(S)-3-{(E)-3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-HYDROXYPROPYL]BENZOATE
    Sodium {1-[({(1S)-1-{3-[(E)-2-(7-chloro-2-quinolinyl)vinyl]phenyl }-3-[2-(2-hydroxy-2-propanyl)phenyl]propyl}sulfanyl)methyl]cyclop ropyl}acetate

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