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mercaptopurine

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Origin: China

Cas No: 50-44-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 50-44-2 Formula: C5H4N4S Molecular Weight: 152.17700

Description

Has a cytotoxicity effect.

Basic Info

Chemical Name	mercaptopurine
Synonyms	1H-Purine-6(9H)-thione; 6-Mercaptopurine; 6H-Purine-6-thione, 1,7-dihydro-; 1,9-Dihydropurine-6-thione DISCONTINUED,see M225450;
CAS No.	50-44-2
Molecular Formula	C5H4N4S
Molecular Weight	152.17700
PSA	89.45000
LogP	1.01550

Properties

Appearance & Physical State	yellow crystalline powder
Density	1.82g/cm3
Melting Point	>313ºC
Flash Point	255.4ºC
Refractive Index	1.828
Storage Condition	Store at RT

Safety Info

Hazard Class	6.1(b)
HS Code	2933599090
Packing Group	III
RIDADR	3249
Signal Word	Danger
Symbol	GHS06
Hazard Declaration	H301

Synthesis Route

6-amino-5-formylamino-3H-pyrimidine-4-thione→mercaptopurine
hypoxanthine→mercaptopurine
N-(4-amino-6-benzylsulfanylpyrimidin-5-yl)formamide→mercaptopurine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - man	40 mg/kg/1W-I	1.Skin and Appendages-dermatitis, other (after systemic exposure)
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	159 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	250 mg/kg	1.Details of toxic effects not reported other than lethal dose value