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Melatonin

Name: Melatonin
Brand: Globalchemmall
SKU: g
Price: 132.0 USD

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FOB Price $132.00

Origin: China

Cas No: 73-31-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Melatonin is an indispensable natural hormone in the human body, which controls and influences the secretion of other hormones.When melatonin in the body is reduced, various functions of the body will be affected, and a variety of diseases will follow.

Product name	Melatonin Powder	CAS NO.	73-31-4
EINECS NO.	200-797-7	Molecular Formula	C13H16N2O2
Appearance	White powder	Purity	99%

Melatonin is a hormone in your body that plays a role in sleep. The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and decreasing when it's light. Melatonin production declines with age. Melatonin is also available as a supplement, typically as an oral tablet. Most melatonin supplements are made in a lab.

People commonly use melatonin for sleep disorders, such as insomnia and jet lag. Unlike with many sleep medications, you are unlikely to become dependent on melatonin, have a diminished response after repeated use (habituation) or experience a hangover effect.

Function:
1. Circadian rhythm sleep disorders in the blind. Melatonin can help improve these disorders in adults and children.
2. Delayed sleep phase (delayed sleep-wake phase sleep disorder). In this disorder your sleep pattern is delayed two hours or more from a conventional sleep pattern, causing you to go to sleep later and wake up later. Research shows that melatonin reduces the length of time needed to fall asleep and advances the start of sleep in young adults and children with this condition. Talk to your child's doctor before giving melatonin to a child.
3. Insomnia. Research suggests that melatonin might provide relief from the inability to fall asleep and stay asleep (insomnia) by slightly improving your total sleep time, sleep quality and how long it takes you to fall asleep.
4. Jet lag. Evidence shows that melatonin can modestly improve jet lag symptoms, such as alertness.
5. Shift work disorder. Some research suggests that melatonin might improve daytime sleep quality and duration in people whose jobs require them to work outside the traditional morning to evening schedule.
6. Sleep-wake cycle disturbances. Melatonin can help treat these disturbances in children with a number of disabilities.

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Please contact with :James Li 0086-15306588542/ 0086-571- 87256576，sales@globalchemmall.com

Q1:	Can I get some samples?
A:	Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2:	How to start orders or make payments?
A:	Proforma invoice will be sent firsty after confirmation of order, enclosed our bank information. Payment by T/T, Western Union
Q3:	What's your MOQ?
A:	Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q4:	How about delivery time?
A:	Delivery time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q5:	Is there a discount?
A:	Different quantity has different discount.
Q6:	How do you treat quality complaint?
A:	First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Certificate

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Property

CAS No.: 73-31-4 Formula: C13H16N2O2 Molecular Weight: 232.27800

Description

Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.

Basic Info

Chemical Name	Melatonin
Synonyms	Melatonine; N-Acetyl-5-methoxy tryptamine; Melatonin; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; primex; Melovine; MLT; N-acetyl-5-methoxytryptamine; Circadin; Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;
CAS No.	73-31-4
Molecular Formula	C13H16N2O2
Molecular Weight	232.27800
PSA	54.12000
LogP	2.24600

Properties

Appearance & Physical State	Off-white powder
Density	1.175g/cm3
Boiling Point	512.8ºC at 760 mmHg
Melting Point	116-120ºC
Flash Point	264ºC
Refractive Index	1.6
Stability	Stable under normal temperatures and pressures.
Storage Condition	-15ºC

Safety Info

RTECS	AC5955000
Safety Statements	S24/25
HS Code	2932999099
WGK Germany	2
Risk Statements	R60
Hazard Codes	T

Synthesis Route

O-methylserotonin+Acetic anhydride→Melatonin
N-acetylserotonin+dimethyl sulfate→Melatonin
N-prop-2-enylacetamide+carbon monoxide→Melatonin

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	1375 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	180 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Subcutaneous	TDLo - Lowest published toxic dose	Rodent - mouse	15 mg/kg/2W-I	1.Blood-pigmented or nucleated red blood cells 2.Blood-changes in erythrocyte (RBC) count 3.Blood-changes in leukocyte (WBC) count