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latanoprost free acid

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Origin: China

Cas No: 41639-83-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 41639-83-2 Formula: C23H34O5 Molecular Weight: 390.51300

    Description

    A metabolite of Latanoprost. Potent, selective FP prostanoid receptor agonist. F-series Prostaglandin analog. 200 times as potent as isopropyl ester form.

    Basic Info

    Chemical Name latanoprost free acid
    Synonyms

    Latanoprost Acid;
    LatanoprostAcid;

    CAS No. 41639-83-2
    Molecular Formula C23H34O5
    Molecular Weight 390.51300
    PSA 97.99000
    LogP 3.31940

    Properties

    Appearance & Physical State Pale yellow oil
    Density 1.159 g/cm3
    Boiling Point 609.1ºC at 760 mmHg
    Flash Point 336.2ºC
    Refractive Index 1.564
    Storage Condition -20ºC

    Synthesis Route

    (Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate→latanoprost free acid
    (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoic acid→latanoprost free acid
    latanoprost→latanoprost free acid

    Precursor

    (3aR,4R,5R,6aS)-4-[(3R)-3-hydroxy-5-phenylpentyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]furan-2,5-diol
    4-carboxybutyl(triphenyl)phosphanium,bromide
    latanoprost
    (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoic acid

    Downstream Product

    ACS 67
    latanoprost

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