Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> lansoprazole

lansoprazole

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 103577-45-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
CAS No.:
103577-45-3
Other Names:
Lansoprazole
MF:
C16H14F3N3O2S
EINECS No.:
103577-45-3
Place of Origin:
Shanghai, China
Type:
Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Antidote, Antipyretic Analgesics and NSAIDs, Auxiliaries and Other Medicinal Chemicals, Disinfectant and Preservatives
Grade Standard:
Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade
Brand Name:
Terppon
Model Number:
101
Purity:
99%
color:
white
Packaging&Delivery
Packaging Details
in 25kg net per drum
Port
shanghai
Lead Time:
1 week

Property

CAS No.: 103577-45-3 Formula: C16H14F3N3O2S Molecular Weight: 369.36100

Description

Lansoprazole is a proton-pump inhibitor (PPI) which inhibits the stomach's production of gastric acids. It is manufactured by a number of companies worldwide under several brand names. In the United States, it was first approved by the Food and Drug Administration (FDA) in 1995. Prevacid patent protection expired on November 10, 2009. There is not evidence that its effectiveness is different than that of other PPIs.
Lansoprazole is a proton-pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPIs available. It is a racemic 1:1 mixture of the enantiomers dexlansoprazole (Dexilant, formerly named Kapidex) and levolansoprazole. Dexlansoprazole is an enantiomerically pure active ingredient of a commercial drug as a result of the enantiomeric shift.
Lansoprazole's plasma elimination half-life (1.5 h) is not proportional to the duration of the drug's effects to the person (i.e. gastric acid suppression). and the effects of the drug last for over 24 hours after it has been used for a day or more. Lansoprazole, given nasogastrically, effectively controls intragastric pH and is an alternative to intravenous pantoprazole in people who are unable to swallow solid-dose formulations.

Basic Info

Chemical Name	lansoprazole
Synonyms	LANSOX; Promp; LANZOR; Ketian; Lansoprazole; Lancid; OGAST; Ulpax; Lanz; Zoton; 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole;
CAS No.	103577-45-3
Molecular Formula	C16H14F3N3O2S
Molecular Weight	369.36100
PSA	87.08000
LogP	4.38090

Properties

Appearance & Physical State	White Crystalline Powder
Density	1.5 g/cm3
Boiling Point	555.8ºC at 760 mmHg
Melting Point	178-182ºC
Flash Point	289.9ºC
Refractive Index	1.591
Storage Condition	2-8ºC
Vapor Pressure	2.55E-10mmHg at 25°C

Safety Info

RTECS	DD9487500
Safety Statements	S26-S36
HS Code	2933990090
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]thio]-1H-benzimidazole→lansoprazole
2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole→lansoprazole
Lansoprazole Sulfide N-Oxide→lansoprazole

Precursor

D-(-)-tartaric acid diethyl ester
Lansoprazole Sulfide N-Oxide
2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]thio]-1H-benzimidazole
2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole

Downstream Product

R-(+)-Lansoprazole
(S)-Lansoprazole

Hot tags: lansoprazole, China, manufacturers, suppliers, factory, wholesale, low price, high quality