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L-homoserine

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Origin: China

Cas No: 672-15-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 672-15-1 Formula: C4H9NO3 Molecular Weight: 119.11900

Description

Homoserine (also called isothreonine) is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2OH. L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by insertion of an additional -CH2- unit into the backbone. Homoserine, or its lactone form, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine.
Homoserine is an intermediate in the biosynthesis of three essential amino acids: methionine, threonine (an isomer of homoserine), and isoleucine. It forms by two reductions of aspartic acid via the intermediacy of aspartate semialdehyde.

Basic Info

Chemical Name	L-homoserine
Synonyms	Butanoic acid, 2-amino-4-hydroxy-, (S)-; H-HOSER-OH; HOMOSERINE-L; S-2-Amino-4-hydroxybutyric acid; L-Homoserine; H-L-HSE-OH; HSE; H-HOSER-OHCL; H-HSE-OH; H-HOMOSER-OH; Homoserine; H-HOMOSERINE;
CAS No.	672-15-1
Molecular Formula	C4H9NO3
Molecular Weight	119.11900
PSA	83.55000
LogP	-0.51900

Properties

Appearance & Physical State	White crystalline powder.
Boiling Point	368.7ºC at 760 mmHg
Melting Point	203ºC
Flash Point	176.8ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at RT.

Safety Info

Safety Statements	S24/25
HS Code	29225000
WGK Germany	3

Synthesis Route

L-methionine→L-homoserine+L-aspartic acid
L-methionine→L-α-aminobutyric acid+L-homoserine
formic acid+L-methionine→L-homoserine+L-aspartic acid

Precursor

L-METHIONINE METHYLSULFONIUM IODIDE
4-[[3-acetamido-5-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]amino]-2-amino-4-oxobutanoic acid
L-methionine
(S)-tert-butyl 1-(furan-2-yl)-3-hydroxypropylcarbamate

Downstream Product

Boc-L-homoserine
(2S)-4-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid
benzyl N-[(3S)-2-oxooxolan-3-yl]carbamate
L-cystathionine

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