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iohexol

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Origin: China

Cas No: 66108-95-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 66108-95-0 Formula: C19H26I3N3O9 Molecular Weight: 821.13800

    Description

    Iohexol is a contrast agent, sold under the trade names Omnipaque and Exypaque; this compound is also sold as a density gradient medium under the names Accudenz, Histodenz and Nycodenz. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
    The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.

    Basic Info

    Chemical Name iohexol
    Synonyms

    omnipaqueTM;
    Exypaque;
    5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide;
    Omnipaque;
    EINECS 266-164-2;
    Omnipaque 240;
    Iohexolum;
    Nycodenz;

    CAS No. 66108-95-0
    Molecular Formula C19H26I3N3O9
    Molecular Weight 821.13800
    PSA 199.89000
    LogP -0.84570

    Properties

    Appearance & Physical State white powder
    Density 2.2 g/cm3
    Boiling Point 891.5ºC at 760 mmHg
    Melting Point 254-256ºC
    Flash Point 493ºC
    Refractive Index 1.724
    Stability Stable at normal temperatures and pressures.
    Storage Condition -20ºC

    Safety Info

    RTECS CZ2205000
    Safety Statements S22-S24/25
    HS Code 2924299090
    WGK Germany 1

    Synthesis Route

    5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide+epichlorohydriniohexol+iodixanol
    5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamideiohexol+iodixanol
    5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide+3-chloropropane-1,2-dioliohexol

    Precursor

    n-Butanol
    epichlorohydrin
    5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
    3-chloropropane-1,2-diol

    Downstream Product

    5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

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