hydroxyzine hydrochloride

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Origin: China

Cas No: 2192-20-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 2192-20-3 Formula: C21H29Cl3N2O2 Molecular Weight: 447.82600

Description

H1 receptor antagonist. Anxiolytic. Antihistaminic.

Basic Info

Chemical Name	hydroxyzine hydrochloride
Synonyms	Disron; Hydroxyzine hydrochloride; Hydroxyzin*2HCl; Arcanax; Hydroxyzine 2HCl; Hydroxyzine dihydrochloride; Vistaject; Vistarex; Quiess; Neurolax; Alamon; 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol,dihydrochloride;
CAS No.	2192-20-3
Molecular Formula	C21H29Cl3N2O2
Molecular Weight	447.82600
PSA	35.94000
LogP	4.53570

Properties

Safety Info

Synthesis Route

1-(4-Chlorobenzhydryl)piperazine+2-(2-Chloroethoxy)ethanol→hydroxyzine hydrochloride

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human - woman	500 ug/kg	1.Behavioral-altered sleep time (including change in righting reflex)
Oral	TDLo - Lowest published toxic dose	Human - man	357 ug/kg	1.Behavioral-altered sleep time (including change in righting reflex)
Unreported	TDLo - Lowest published toxic dose	Human - child	750 ug/kg	1.Skin and Appendages-dermatitis, other (after systemic exposure)