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Hexetidine

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Origin: China

Cas No: 141-94-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 141-94-6 Formula: C21H45N3 Molecular Weight: 339.60200

    Description

    Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.
    Hexetidine is the medicinal ingredient in Sterisol, which is labelled for the symptomatic treatment of streptococcal pharyngitis ('strep throat'), tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery.
    In the UK, hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. In Canada, hexetidine is the active ingredient in the medicated mouthwash branded Steri/sol. The product called Sterisol in Canada is no longer available it has been discontinued. This is produced by Mcneil, a division of Johnson & Johnson. Oraldene contains 0.1g/100ml of hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40ml named Hexoral (by Mcneil) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash Bactidol (by Mcneil) which is sold in many Asian countries. In Germany, hexetidine vaginal suppositories branded Vagi-Hex are in use for vaginal antisepsis. They are also used in late pregnancy for reducing neonatal infectious mortality and morbidity due to group B streptococcal infections; nonetheless, hexetidine is to be used only with care during pregnancy, and its vaginal use is counter-indicated in the first three months of pregnancy.
    Hexetidine

    Basic Info

    Chemical Name Hexetidine
    Synonyms

    1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine;

    CAS No. 141-94-6
    Molecular Formula C21H45N3
    Molecular Weight 339.60200
    PSA 32.50000
    LogP 5.28780

    Properties

    Density 0.889
    Boiling Point 160ºC (0.4 mmHg)
    Flash Point 70ºC
    Refractive Index 1.4649
    Vapor Pressure 3.11E-06mmHg at 25°C

    Safety Info

    Safety Statements S26-S36
    HS Code 2933599090
    Risk Statements R36/37/38
    Hazard Codes Xi
    Hazard Declaration H315; H319; H335
    Symbol GHS07
    Caution Statement P261; P305 + P351 + P338
    Signal Word Warning

    Synthesis Route

    1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-nitropyrimidineHexetidine

    Precursor

    1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-nitropyrimidine

    Downstream Product

    2,6-bis(2-ethylhexyl)-7a-methyl-1,3,5,7-tetrahydroimidazo[1,5-c]imidazole
    1-N,3-N-bis(2-ethylhexyl)-2-methylpropane-1,2,3-triamine

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