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guanine

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Origin: China

Cas No: 73-40-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
73-40-5
Other Names:
Guanine
MF:
/
EINECS No.:
/
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates, Antibiotic and Antimicrobial Agents
Purity:
99%min, 99%, 99%min, 100%, 99%, 98%
Application:
Animal Pharmaceuticals, Pharmaceutical Raw Intermediates
Appearance:
White
Model Number:
TOP
Color:
White
Grade Standard:
Medicine Grade
Grade:
Phamaceutical Grade
Shelf life:
2years
Assay:
HPLC 99%
Certificate:
ISO
Packaging&Delivery
Packaging Details
1g/bag, 5g/bag, 10g/bag, 100g/bag and 1kg/bag or according to to your requirements
Lead Time:
Quantity(Grams) 1 - 100000 >100000
Est. Time(days) 3 To be negotiated

Property

CAS No.: 73-40-5 Formula: C5H5N5O Molecular Weight: 151.12600

Description

Guanine (G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine.
With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Being unsaturated, the bicyclic molecule is planar.

Basic Info

Chemical Name	guanine
Synonyms	2-amino-6-oxypurine; 6H-Purin-6-one, 2-amino-1,7-dihydro-; Guanin; 2-amino-6-hydroxypurine; Guanie; 2-amino-1,7-dihydro-6H-purin-6-one; dewpearl; 2-amino-1,9-dihydro-6H-purin-6-one; Guanine; quanine; Gua; guamine;
CAS No.	73-40-5
Molecular Formula	C5H5N5O
Molecular Weight	151.12600
PSA	100.45000
LogP	-0.19040

Properties

Appearance & Physical State	white to light yellow crystal powder
Density	2.19 g/cm3
Boiling Point	591.4ºC at 760 mmHg
Melting Point	360ºC
Flash Point	311.4ºC
Refractive Index	2.047
Water Solubility	practically insoluble
Stability	Stable. Incompatible with strong oxidizing agents.
Storage Condition	2-8ºC

Safety Info

RTECS	MF8260000
Safety Statements	S26-S37/39
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

guanosine→guanine+aldehydo-D-ribose
2'-deoxyguanosine→guanine+N-(2,6-diamino-4-oxo-1H-pyrimidin-5-yl)formamide
dGMP→guanine+2'-deoxyguanosine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD - Lethal dose	Rodent - mouse	>3333 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD - Lethal dose	Rodent - mouse	>1 gm/kg	1.Details of toxic effects not reported other than lethal dose value
Subcutaneous	TDLo - Lowest published toxic dose	Rodent - rat	1300 mg/kg/26W-I	1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria 2.Skin and Appendages-tumors 3.Reproductive-Tumorigenic effects-ovarian tumors

Precursor

6-benzylsulfanyl-7H-purin-2-amine
acyclovir
2,6-diamino-5-nitroso-1H-pyrimidin-4-one
2-(acetylamino)-6-(diphenylcarbamoyl)-9-[N-(1,3-dipivaloyloxyprop-2-yl)acetylaminomethyl]-9H-purine

Downstream Product

N-benzyl-2-chloro-7H-purin-6-amine
penciclovir
2-amino-8-bromo-3,7-dihydropurin-6-one
2-amino-9-[(1-chloro-3-hydroxypropan-2-yl)oxymethyl]-3H-purin-6-one

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