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Picture of Granisetron hydrochloride

Granisetron hydrochloride

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Origin: China

Cas No: 107007-99-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    107007-99-8
    Other Names:
    Granisetron hydrochloride
    MF:
    C18H25ClN4O
    EINECS No.:
    107007-99-8
    Place of Origin:
    Shanghai, China
    Grade Standard:
    Electron Grade, Food Grade, Industrial Grade, Medicine Grade, Reagent Grade
    Purity:
    99.0%min
    Appearance:
    powder
    Application:
    Medicine
    Brand Name:
    TERPPON
    Model Number:
    502
    color:
    white

    Packaging&Delivery

    Packaging Details
    in 25kg drum
    Port
    Shanghai
    Lead Time:
    1 week
  • Property

    CAS No.: 107007-99-8 Formula: C18H25ClN4O Molecular Weight: 348.87000

    Description

    A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor

    Basic Info

    Chemical Name Granisetron hydrochloride
    Synonyms

    Granisetron Hydrochloride;
    1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide;
    1-methyl-N-[(1S,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide,hydrochloride;

    CAS No. 107007-99-8
    Molecular Formula C18H25ClN4O
    Molecular Weight 348.87000
    PSA 50.16000
    LogP 3.44920

    Properties

    Appearance & Physical State White to Off-White Crystalline Solid
    Density 1.33g/cm3
    Boiling Point 532ºC at 760mmHg
    Melting Point 290-292ºC
    Flash Point 275.6ºC
    Refractive Index 1.69
    Storage Condition Room temp
    Vapor Pressure 0mmHg at 25°C

    Safety Info

    RTECS NK7882200
    Safety Statements S26; S36; S37
    HS Code 2933990090
    Risk Statements R22
    Hazard Codes Xn; Xi

    Synthesis Route

    granisetronGranisetron hydrochloride
    exo-3-Amino-9-methyl-9-azabicyclo[3,3,1]nonane+1-methylindazole-3-carbonyl chlorideGranisetron hydrochloride

    Precursor

    granisetron
    1-methylindazole-3-carbonyl chloride
    exo-3-Amino-9-methyl-9-azabicyclo[3,3,1]nonane

    Downstream Product

    granisetron

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