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Goserelin

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Origin: China

Cas No: 65807-02-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property
CAS No.: 65807-02-5 Formula: C59H79D5N18O14 Molecular Weight: 1274.44000

Description
Goserelin acetate (trade name Zoladex, by AstraZeneca) is a drug used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer. It is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist.
Structurally, it is a decapeptide. It is the natural LHRH/GnRH decapeptide with two substitutions to inhibit rapid degradation.
Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production.
Zoladex was approved by the U.S. Food and Drug Administration in 1989 for treatment of prostate cancer.

Basic Info

Chemical Name Goserelin

Synonyms

CAS No. 65807-02-5

Molecular Formula C59H79D5N18O14

Molecular Weight 1274.44000

PSA 493.39000

LogP 2.78000

Properties

Appearance & Physical State white solid

Density 1.5 g/cm3

Refractive Index 1.692

Storage Condition -20ºC

Safety Info

Safety Statements S22-S24/25

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