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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> gabapentin enacarbil
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gabapentin enacarbil

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Origin: China

Cas No: 478296-72-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 478296-72-9 Formula: C16H27NO6 Molecular Weight: 329.38900

    Basic Info

    Chemical Name gabapentin enacarbil
    Synonyms

    {[(1-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexaneacetic acid;
    Solzira;
    UNII-75OCL1SPBQ;
    2-[1-[[1-(2-methylpropanoyloxy)ethoxycarbonylamino]methyl]cyclohexyl]acetic acid;
    Horizant;
    ASP-8825;
    Gabapentin enacarbil;

    CAS No. 478296-72-9
    Molecular Formula C16H27NO6
    Molecular Weight 329.38900
    PSA 101.93000
    LogP 3.07390

    Properties

    Density 1.134
    Boiling Point 482.021ºC at 760 mmHg
    Melting Point 65ºC

    Synthesis Route

    1-[(2,5-dioxopyrrolidinyl)oxycarbonyloxy]ethyl 2-methylpropanoate+gabapentin→gabapentin enacarbil
    1-[(chlorocarbonyl)oxy]ethyl 2-methylpropionate+gabapentin→gabapentin enacarbil
    gabapentin+1-(4-nitrophenoxy)carbonyloxyethyl 2-methylpropanoate→gabapentin enacarbil

    Precursor

    1-(4-nitrophenoxy)carbonyloxyethyl 2-methylpropanoate
    1-[(2,5-dioxopyrrolidinyl)oxycarbonyloxy]ethyl 2-methylpropanoate
    1-{[(α-chloroethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid
    1-[(chlorocarbonyl)oxy]ethyl 2-methylpropionate

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