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Ezlopitant

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Origin: China

Cas No: 147116-64-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 147116-64-1 Formula: C31H38N2O Molecular Weight: 454.64600

    Description

    Ezlopitant (CJ-11,974) is an NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome but it appears to have been discontinued.

    Basic Info

    Chemical Name Ezlopitant
    Synonyms

    (2S,3S)-2-Diphenylmethyl-3-[(5-isopropyl-2-methoxybenzyl)amino]quinuclidine;
    (2S,3S)-2-(Diphenylmethyl)-N-(5-isopropyl-2-methoxybenzyl)quinuclidin-3-amine;
    CJ-11974;

    CAS No. 147116-64-1
    Molecular Formula C31H38N2O
    Molecular Weight 454.64600
    PSA 24.50000
    LogP 6.53190

    Properties

    Density 1.12g/cm3
    Boiling Point 570.3ºC at 760mmHg
    Flash Point 298.7ºC
    Refractive Index 1.614
    Vapor Pressure 5.08E-13mmHg at 25°C

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