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Everolimus

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Origin: China

Cas No: 159351-69-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 159351-69-6 Formula: C53H83NO14 Molecular Weight: 958.22400

Description

Everolimus (INN) (earlier code name RAD001) is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR).
It is currently used as an immunosuppressant to prevent rejection of organ transplants and treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
It is marketed by Novartis under the tradenames Zortress (USA) and Certican (Europe and other countries) in transplantation medicine, and as Afinitor (general tumours) and Votubia (tumours as a result of TSC) in oncology. Everolimus is also available from Biocon, with the brand name Evertor.

Basic Info

Chemical Name	Everolimus
Synonyms	Zortress; Certican; CERTICAN(R); 42-O-(2-Hydroxyethyl)-rapamycin; Afinitor; RAD-001; SDZRAD; Certica;
CAS No.	159351-69-6
Molecular Formula	C53H83NO14
Molecular Weight	958.22400
PSA	204.66000
LogP	6.13510

Properties

Appearance & Physical State	Off-white to light yellow powd
Density	1.18 g/cm3
Boiling Point	998.7ºC at 760 mmHg
Flash Point	557.8ºC
Refractive Index	1.548
Storage Condition	-20ºC
Vapor Pressure	0mmHg at 25°C