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Etozolin

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Origin: China

Cas No: 73-09-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 73-09-6 Formula: C13H20N2O3S Molecular Weight: 284.37500

Description

Etozolin (Diulozin, Elkapin, Etopinil) is a loop diuretic used in Europe.

Basic Info

Chemical Name	Etozolin
Synonyms	3-Methyl-5-piperidino-2-ethoxycarbonylmethylen-thiazolidon-(4); Elkapin; [3-Methyl-4-oxo-5-(1-piperidinyl)thiazolidin-2-ylidene]acetic acid ethyl ester; 2-ethoxycarbonylmethylene-3-methyl-5-piperidino-4-thiazolidone; [3-Methyl-4-oxo-5-(1-piperidinyl)thiazolidin-2-ylidene]acetic acid ethyl; W-2900A; (3-methyl-4-oxo-5-piperidin-1-yl-thiazolidin-2-ylidene)-acetic acid ethyl ester;
CAS No.	73-09-6
Molecular Formula	C13H20N2O3S
Molecular Weight	284.37500
PSA	75.15000
LogP	1.28390

Properties

Density	1.288g/cm3
Boiling Point	449.4ºC at 760 mmHg
Flash Point	225.6ºC
Refractive Index	1.614

Synthesis Route

ethyl 2-(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)acetate→Etozolin
Piperidine+(5-bromo-3-methyl-4-oxo-thiazolidin-2-ylidene)-acetic acid ethyl ester→Etozolin

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	10250 mg/kg	1.Sense Organs and Special Senses (Eye)-ptosis 2.Behavioral-somnolence (general depressed activity) 3.Behavioral-ataxia
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1575 mg/kg	1.Sense Organs and Special Senses (Eye)-ptosis 2.Behavioral-somnolence (general depressed activity) 3.Behavioral-ataxia
Intravenous	LDLo - Lowest published lethal dose	Rodent - rat	110 mg/kg	1.Sense Organs and Special Senses (Eye)-ptosis 2.Behavioral-somnolence (general depressed activity) 3.Behavioral-ataxia