Home > Aromatic Compounds> Ethyl 7-nitroindole-2-carboxylate

Ethyl 7-nitroindole-2-carboxylate

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Origin: China

Cas No: 6960-46-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 6960-46-9 Formula: C11H10N2O4 Molecular Weight: 234.20800

Description

Ethyl 7-Nitroindole-2-carboxylate is used to prepare aryl(indolyl)oxadiazoles via Fischer indole synthesis of pyruvate nitrophenylhydrazones. It is also used to synthesize p38 Inhibitors.

Basic Info

Chemical Name	Ethyl 7-nitroindole-2-carboxylate
Synonyms	ethyl 7-nitro-1H-indole-2-carboxylate;
CAS No.	6960-46-9
Molecular Formula	C11H10N2O4
Molecular Weight	234.20800
PSA	87.91000
LogP	2.77600

Properties

Appearance & Physical State	yellow to brown powder
Density	1.393 g/cm3
Boiling Point	429.5ºC at 760 mmHg
Melting Point	90-96ºC
Flash Point	213.5ºC
Refractive Index	1.652

Safety Info

Safety Statements	24/25
HS Code	2933990090
Hazard Codes	Xi

Synthesis Route

ethyl 2-[2-(2-nitrophenyl)hydrazinylidene]propanoate→Ethyl 7-nitroindole-2-carboxylate
(Z)-ethyl pyruvate 2-(2-nitrophenyl)hydrazone→Ethyl 7-nitroindole-2-carboxylate
(E)-ethyl pyruvate 2-(2-nitrophenyl)hydrazone→Ethyl 7-nitroindole-2-carboxylate

Precursor

Ethyl pyruvate
(Z)-ethyl pyruvate 2-(2-nitrophenyl)hydrazone
ethyl 2-[2-(2-nitrophenyl)hydrazinylidene]propanoate
2-Nitrophenylhydrazine hydrochloride

Downstream Product

7-Nitroindole-2-carboxylic acid
7-nitro-1H-indole
1H-indol-7-amine

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