Doxylamine succinate salt

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Origin: China

Cas No: 562-10-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 562-10-7 Formula: C21H28N2O5 Molecular Weight: 388.45700

Description

H1 Histamine receptor antagonist. Antihistaminic; sedative; hypnotic.

Basic Info

Chemical Name	Doxylamine succinate salt
Synonyms	butanedioic acid,N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine;
CAS No.	562-10-7
Molecular Formula	C21H28N2O5
Molecular Weight	388.45700
PSA	99.96000
LogP	2.85910

Properties

Appearance & Physical State	white to light cream powder
Density	1.043g/cm3
Boiling Point	364.9ºC at 760 mmHg
Melting Point	103 - 108ºC
Flash Point	174.5ºC
Stability	Stable, but may be light sensitive. Incompatible with strong oxidizing agents, acids, bases.
Storage Condition	Refrigerator

Safety Info

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LDLo - Lowest published lethal dose	Rodent - rat	600 mg/kg	1.Behavioral-convulsions or effect on seizure threshold 2.Behavioral-food intake (animal) 3.Nutritional and Gross Metabolic-weight loss or decreased weight gain
Subcutaneous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	440 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	470 mg/kg	1.Behavioral-convulsions or effect on seizure threshold