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Doxepin Hydrochloride

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Origin: China

Cas No: 1229-29-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 1229-29-4 Formula: C19H22ClNO Molecular Weight: 315.83700

Description

Doxepin is used clinically to treat anxiety and depression. Doxepin is an antidepressant.

Basic Info

Chemical Name	Doxepin Hydrochloride
Synonyms	11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]oxepine Hydrochloride; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride; Doxepin hydrochloride;
CAS No.	1229-29-4
Molecular Formula	C19H22ClNO
Molecular Weight	315.83700
PSA	12.47000
LogP	4.76440

Properties

Appearance & Physical State	white to off-white powder
Boiling Point	413.3ºC at 760mmHg
Flash Point	121.3ºC
Vapor Pressure	4.87E-07mmHg at 25°C

Safety Info

Hazard Class	6.1(b)
Safety Statements	36/37/39-45
HS Code	2932999099
Packing Group	III
RIDADR	UN 2811 6.1/PG 3
Risk Statements	R25

Synthesis Route

2-Phenoxymethylbenzoic Acid→Doxepin Hydrochloride
sodium phenolate→Doxepin Hydrochloride
ETHYL 2-(BROMOMETHYL)BENZOATE→Doxepin Hydrochloride

Precursor

ETHYL 2-(BROMOMETHYL)BENZOATE
sodium phenolate
2-Phenoxymethylbenzoic Acid
Dibenzo[b,e]oxepin-11(6H)-one

Downstream Product

(E)-N-acetyldidesmethyldoxepin
N-[(3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)propyl]-N-methylformamide
Dibenzo[b,e]oxepin-11(6H)-one
N-[(3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)propyl]-N-methylacetamide

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