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DL-Isoserine

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Origin: China

Cas No: 565-71-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 565-71-9 Formula: C3H7NO3 Molecular Weight: 105.09300

Description

DL-Isoserine has been used in the synthesis of L-isoserine derivatives as aminopeptidase N inhibitors.

Basic Info

Chemical Name	DL-Isoserine
Synonyms	5-Oxo-L-proline 1-methylethyl ester; L-Pyroglutamic acid isopropyl ester; isopropyl 5-oxo-L-prolinate; pyroglutamic acid iso-propyl ester; 3-Amino-2-hydroxypropionic acid;
CAS No.	565-71-9
Molecular Formula	C3H7NO3
Molecular Weight	105.09300
PSA	83.55000
LogP	-0.90910

Properties

Density	1.415g/cm3
Boiling Point	386.6ºC at 760mmHg
Melting Point	235ºC (dec.)
Flash Point	187.6ºC
Refractive Index	1.519

Safety Info

Safety Statements	S22-S24/25

Synthesis Route

(S)-2-hydroxy-3-nitropropionic acid→DL-Isoserine
(S)-2-oxazolidinone-5-carboxylic acid benzyl ester→DL-Isoserine
(2S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxypropanoic acid→DL-Isoserine

Precursor

(S)-2-oxazolidinone-5-carboxylic acid benzyl ester
(S)-2-hydroxy-3-nitropropionic acid
(+)-ethyl N,O-diacetyl-3-amino-2-hydroxypropionate
O-[3-amino-(2S)-t-butyldimethylsilyloxypropanoyl]-(1'R,2'S,5'R)-8'phenylmenthol

Downstream Product

(2S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

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