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(2R,3S)-3-Phenylisoserine

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Origin: China

Cas No: 136561-53-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 136561-53-0 Formula: C9H11NO3 Molecular Weight: 181.18900

Basic Info

Chemical Name	(2R,3S)-3-Phenylisoserine
Synonyms	(2R,3S)-3-amino-2-hydroxy-3-phenylpropionic acid; (2R,3S)-3-phenyl-isoserine; (2R,3S)-3-AMINO-2-HYDROXY-3-PHENYL-PROPANOIC ACID; (2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid; 3-(2R,3S)-PHENYLISOSERINE; (2R,3S)-2-hydroxy-3-aMino-3-phenylpropionic acid; (2R,3S)-3-Amino-2-hydroxy-3-phenylpropanic acid; H-ISE(3-PHENYL)-OH;
CAS No.	136561-53-0
Molecular Formula	C9H11NO3
Molecular Weight	181.18900
PSA	83.55000
LogP	0.83220

Properties

Density	1.335
Boiling Point	360.6ºC at 760mmHg
Flash Point	171.9ºC
Refractive Index	1.593
Storage Condition	2-8ºC
Vapor Pressure	7.87E-06mmHg at 25°C

Synthesis Route

(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one→(2R,3S)-3-Phenylisoserine
2-Azetidinone, 4-phenyl-3-(phenylmethoxy)-, (3R-cis)-→(2R,3S)-3-Phenylisoserine
(3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylazetidin-2-one→(2R,3S)-3-Phenylisoserine

Precursor

(3R,4S)-3-Hydroxy-4-phenylazetidin-2-one
(3R,4S)-3-benzyloxy-1-[(2S)-2-(1-ethyl-1-methoxypropyl)pyrrolidin-1-yl]-4-phenylazetidin-2-one
2-Azetidinone, 4-phenyl-3-(phenylmethoxy)-, (3R-cis)-
(3R,4S)-cis-3-benzyloxy-1-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]-4-phenylazetidin-2-one

Downstream Product

(2R,3S)-N-Benzoyl-3-phenyl Isoserine
(4S,5R)-3-Benzoyl-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid
(4S,5R)-2,4-Diphenyl-4,5-dihydrooxazole-5-carboxylic acid
methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate

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