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diphacinone

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Origin: China

Cas No: 82-66-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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CAS No.: 82-66-6 Formula: C23H16O3 Molecular Weight: 340.37100

Description

Diphenadione is a vitamin K antagonist that has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents. The chemical compound is an anti-coagulant with active half-life[verification needed] longer than warfarin and other synthetic indandione anticoagulants.[bettersourceneeded]; It is toxic to mammals, in all forms, to all modes of contact, including via skin; exposure and oral ingestion of the toxin may cause irregular heartbeat and major maladies associated with its impact on blood clotting, depending on dose.[verification needed][bettersourceneeded] As a "second-generation" anticoagulant, diphenadione is more toxic than the first generation compounds (e.g., warfarin).:436 For purposes of treating toxicity on exposure, diphenadione is grouped with other vitamin K antagonists (coumarins and indandiones); despite being directed at rodents and being judged as less hazardous to humans and domestic animals than other rodenticides in use (by the U.S. Environmental Protection Agency), indandione anticoagulants, nevertheless, "may cause human toxicity at a much lower dose than conventional 'first-generation anticoagulants'… and can bioaccumulate in the liver.":173

Basic Info

Chemical Name	diphacinone
Synonyms	Oragulant; difenadione; Diphenandione; Didandin; Diphenacin; 2-diphenylacetyl-1,3-indandione; 2-(2,2-diphenylacetyl)indene-1,3-dione; 2-(diphenylacetyl)-1H-indene-1,3(2H)-dione; Diphenadion; 1H-Indene-1,3(2H)-dione, 2-(diphenylacetyl)-; diphacin; Promar; Dipaxin; 2-(2,2-diphenylacetyl)-1H-indene-1,3(2H)-dione; diphenadione; 2-(diphenylacetyl)indan-1,3-dione;
CAS No.	82-66-6
Molecular Formula	C23H16O3
Molecular Weight	340.37100
PSA	51.21000
LogP	4.08300

Properties

Density	1.281(25ºC)
Boiling Point	528.7ºC at 760 mmHg
Melting Point	145-147ºC
Refractive Index	1.643

Safety Info

RTECS	NK5600000
Hazard Class	6.1(a)
Safety Statements	S36/37; S45
HS Code	2914399013
Packing Group	I
RIDADR	UN 2811
Risk Statements	R28
Hazard Codes	T+

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1500 ug/kg	1.Details of toxic effects not reported other than lethal dose value
Inhalation	LC50 - Lethal concentration, 50 percent kill	Rodent - rat	2 gm/m3/4H	1.Details of toxic effects not reported other than lethal dose value
Administration onto the skin	LD50 - Lethal dose, 50 percent kill	Rodent - rat	200 mg/kg	1.Details of toxic effects not reported other than lethal dose value