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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate
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Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate

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Origin: China

Cas No: 50428-14-3

Specification: 99%min

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 50428-14-3 Formula: C17H16N2O5 Molecular Weight: 328.31900

    Description

    A photodegradation product of Nifedipine. Shown to relax contractions of the rat aortic strip induced by norepinephrine and other agonists.

    Basic Info

    Chemical Name Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate
    Synonyms

    dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate;
    Nifedipine Nitrosophenylpyridine Analog;
    Dehydronitroso Nifedipine;
    Nifedipine impurity B;

    CAS No. 50428-14-3
    Molecular Formula C17H16N2O5
    Molecular Weight 328.31900
    PSA 94.92000
    LogP 3.33650

    Properties

    Density 1.26g/cm3
    Boiling Point 449ºC at 760 mmHg
    Flash Point 225.3ºC
    Refractive Index 1.579

    Safety Info

    HS Code 2933399090

    Synthesis Route

    nifedipine→Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate
    nifedipine→Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate+dimer of 2,6-dimethyl-3,5-di(carbomethoxy)-4-(2'-nitrosophenyl)pyridine
    2-nitrobenzaldehyde→Dimethyl 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylate

    Precursor

    Methyl acetoacetate

    nifedipine
    methyl (E)-3-aminobut-2-enoate

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