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DIETHYLSTILBESTROL DIPROPIONATE

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Origin: China

Cas No: 130-80-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 130-80-3 Formula: C24H28O4 Molecular Weight: 380.47700

    Description

    Diethylstilbestrol dipropionate (brand names Agostilben, Biokeral, Clinestrol, Cyclen, Estilbin, Estril, Neobenzoestrol, Orestol, Oroestrol, Ostregenin, Prostilbene, Stilbestriol DP, Stilboestrolum Dipropionicum, Stilboestrol, Synestrin, Willestrol, others), or diethylstilbestrol dipropanoate, also known as stilboestrol dipropionate (BANM), is a synthetic, non-steroidal estrogen that was formerly marketed widely throughout Europe. It is an ester of diethylstilbestrol with propionic acid. The drug is one of the most potent estrogens known.

    Basic Info

    Chemical Name DIETHYLSTILBESTROL DIPROPIONATE
    Synonyms

    Dibestil;
    Desd;
    Estroben;
    Phenol, 4,4‘-(1,2-diethyl-1,2-ethenediyl)bis-, dipropanoate, (E)-;
    cyrenb;
    Estilbin;
    Gynolett;
    Horfemine;
    Euvestin;
    Orestol;

    CAS No. 130-80-3
    Molecular Formula C24H28O4
    Molecular Weight 380.47700
    PSA 52.60000
    LogP 6.04820

    Properties

    Density 1.075g/cm3
    Boiling Point 486.4ºC at 760mmHg
    Flash Point 237ºC
    Refractive Index 1.542
    Vapor Pressure 1.29E-09mmHg at 25°C

    Safety Info

    Hazard Class 6.1(b)
    HS Code 2917399090
    Packing Group III
    RIDADR UN 3249
    Risk Statements R45; R46; R61; R20/21/22
    Hazard Codes T

    Synthesis Route

    3.4-bis-(4-propionyloxy-phenyl)-hexadiene-(2t.4t)→DIETHYLSTILBESTROL DIPROPIONATE
    Diethylstilbestrol+Propionic anhydride→DIETHYLSTILBESTROL DIPROPIONATE
    E,E-Dienestrol→DIETHYLSTILBESTROL DIPROPIONATE

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous TDLo - Lowest published toxic dose Rodent - rat 80 mg/kg 1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria
    2.Endocrine-tumors
    3.Endocrine-changes in growth hormone
    Implant TDLo - Lowest published toxic dose Rodent - rat 113 mg/kg 1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria
    2.Endocrine-tumors
    Implant TDLo - Lowest published toxic dose Rodent - guinea pig 5 mg/kg 1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria
    2.Reproductive-Tumorigenic effects-other reproductive system tumors

    Precursor

    (4-propanoylphenyl) propanoate
    3.4-bis-(4-propionyloxy-phenyl)-hexadiene-(2t.4t)
    E,E-Dienestrol
    Propionic anhydride

    Downstream Product

    DIETHYLSTILBESTROL DIMETHYL ETHER
    (Z)-4,4'-(hex-3-ene-3,4-diyl)diphenol
    DIETHYLSTILBESTROL DIPROPIONATE
    (Z)-3,4-Bis(4-methoxyphenyl)-3-hexen

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