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deserpidine

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Origin: China

Cas No: 131-01-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    131-01-1
    Other Names:
    Deserpidine
    MF:
    C32H38N2O8
    EINECS No.:
    205-004-8
    Place of Origin:
    Shandong, China
    Type:
    Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    99.0%min
    Brand Name:
    QDxigema
    Model Number:
    TOP
    Application:
    USED
    Appearance:
    white crystal powder, White to Off White Crystalline powder
    Product Name:
    Deserpidine
    CAS:
    131-01-1
    Color:
    White to Off White
    Molecular Weight:
    578.66
    Density:
    1.32 g/cm3
    B.P.:
    676.1 °C at 760 mmHg
    Refractive index:
    1.625
    Shelf life:
    2 Years
    Package:
    Aluminum Foil Bag

    Packaging&Delivery

    Packaging Details
    25kg/fiber drum, or 25kg/carton
    Port
    QINGDAO PORT

  • Property

    CAS No.: 131-01-1 Formula: C32H38N2O8 Molecular Weight: 578.65300

    Description

    Deserpidine (INN) is an antihypertensive drug related to reserpine which occurs naturally in Rauvolfia spp.

    Basic Info

    Chemical Name deserpidine
    Synonyms

    17-methoxy-18-(3,4,5-trimethoxy-benzoyloxy)-yohimbane-16-carboxylic acid methyl ester;
    Yohimban-16-carboxylic acid, 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3α,16α,17-,18α,20-)-;
    methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;
    Canescine;
    Deserpidin;
    Recanescine;
    Deserpidine;
    Desepridine;
    Raunormin;
    Canescin;
    Recanescin;
    Raunormine;
    Harmonyl;

    CAS No. 131-01-1
    Molecular Formula C32H38N2O8
    Molecular Weight 578.65300
    PSA 108.55000
    LogP 4.10040

    Properties

    Appearance & Physical State white crystal powder
    Density 1.32 g/cm3
    Boiling Point 676.1ºC at 760 mmHg
    Melting Point ~275 °C (dec.)(lit.)
    Flash Point 362.7ºC
    Refractive Index 1.625
    Vapor Pressure 3.87E-18mmHg at 25°C

    Safety Info

    WGK Germany 3
    RIDADR UN 9111

    Synthesis Route

    3,4,5-Trimethoxybenzoyl chloride+→deserpidine
    3,4,5-Trimethoxybenzoyl chloride→deserpidine
    tryptamine→deserpidine

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 15 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse 500 mg/kg 1.Behavioral-coma
    2.Lungs, Thorax, or Respiration-dyspnea
    3.Gastrointestinal-hypermotility, diarrhea
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 60 mg/kg 1.Behavioral-coma
    2.Lungs, Thorax, or Respiration-dyspnea
    3.Gastrointestinal-hypermotility, diarrhea

    Precursor

    3,4,5-Trimethoxybenzoyl chloride
    tryptamine

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