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dasabuvir

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Origin: China

Cas No: 1132935-63-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1132935-63-7 Formula: C26H27N3O5S Molecular Weight: 493.57500

    Basic Info

    Chemical Name dasabuvir
    Synonyms

    Methanesulfonamide,N-(6-(5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl)-2-naphthalenyl);
    ABT333;
    N-[6-[3-tert-butyl-5-(2,4-dioxopyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl]methanesulfonamide;
    N-(6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide;
    Dasabuvir;

    CAS No. 1132935-63-7
    Molecular Formula C26H27N3O5S
    Molecular Weight 493.57500
    PSA 118.90000
    LogP 5.58970

    Synthesis Route

    1-(3-tert-butyl-5-iodo-4-methoxyphenyl)pyrimidine-2,4-dione+N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide→dasabuvir
    1-(3-tert-butyl-5-iodo-4-methoxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione+N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide→dasabuvir
    Methanesulfonamide+6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate→dasabuvir

    Precursor

    6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
    1-(3-tert-butyl-5-iodo-4-methoxyphenyl)pyrimidine-2,4-dione
    N-(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide
    Methanesulfonamide

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