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Origin: China

Cas No: 3546-03-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods


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    CAS No.: 3546-03-0 Formula: C19H21N3S Molecular Weight: 323.45500


    Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class which was introduced by Theraplix in France in 1972 and later in Portugal as well. It is used for the treatment of schizophrenia and, especially, for psychosis-associated anxiety, due to its unique anxiolytic efficacy.
    Cyamemazine differs from other phenothiazine neuroleptics in that aside from the usual profile of dopamine, α1-adrenergic, H1, and mACh receptor antagonism, it additionally produces potent blockade of several serotonin receptors, including 5-HT2A, 5-HT2C, and 5-HT7. These actions have been implicated in cyamemazine's anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A), and despite being classified as a typical, it actually behaves like an atypical antipsychotic.

    Basic Info

    Chemical Name Cyamemazine

    10H-Phenothiazine-2-carbonitrile, 10-[3-(dimethylamino)-2-methylpropyl]-;

    CAS No. 3546-03-0
    Molecular Formula C19H21N3S
    Molecular Weight 323.45500
    PSA 55.57000
    LogP 4.42368


    Density 1.21 g/cm3
    Boiling Point 479ºC at 760mmHg
    Flash Point 243.5ºC
    Refractive Index 1.654

    Safety Info

    HS Code 2934300000
    Signal Word Warning
    Symbol GHS09
    Hazard Declaration H410
    Caution Statement P273; P501

    Synthesis Route

    cyamemazine N-oxide10-[2-methyl-3-(methylamino)propyl]phenothiazine-2-carbonitrile+Cyamemazine
    10H-Phenothiazine-2-carboxylic acidCyamemazine
    10H-phenothiazine-2-carboxylic acid amideCyamemazine


    10H-phenothiazine-2-carboxylic acid amide
    cyamemazine N-oxide

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