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chlorambucil

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Origin: China

Cas No: 305-03-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 305-03-3 Formula: C14H19Cl2NO2 Molecular Weight: 304.21200

    Description

    Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent and can be given orally.
    It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

    Basic Info

    Chemical Name chlorambucil
    Synonyms

    4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid;
    Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-;
    Chlorambucil;
    4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid 4-[Bis(2-chloroethyl)amino]benzenebutyric acid;

    CAS No. 305-03-3
    Molecular Formula C14H19Cl2NO2
    Molecular Weight 304.21200
    PSA 40.54000
    LogP 3.37790

    Properties

    Appearance & Physical State beige powder
    Density 1.248 g/cm3
    Boiling Point 460.1ºC at 760 mmHg
    Melting Point 64ºC
    Flash Point 232.1ºC
    Refractive Index 1.536
    Stability Stable, but may be light sensitive. Store cold. Incompatible with strong oxidizing agents.
    Storage Condition 2-8ºC

    Safety Info

    RTECS ES7525000
    Hazard Class 6.1(b)
    Safety Statements S53-S26-S45
    HS Code 2922499990
    WGK Germany 3
    Packing Group III
    RIDADR UN 2811
    Risk Statements R45; R25; R36/37/38
    Hazard Codes T
    Hazard Declaration H301; H315; H319; H335; H350
    Signal Word Danger
    Symbol GHS06, GHS08
    Caution Statement P201; P261; P301 + P310; P305 + P351 + P338; P308 + P313

    Downstream Product

    17β-hydroxy-2a-aza-A-homo-5α-androstan-4-one p-<N,N-bis(2-chloroethyl)amino>phenylbutyrate ester
    N-[3-[4-[bis(2-chloroethyl)amino]phenyl]propyl]acridin-9-amine
    17β-hydroxy-3a-aza-A-homo-5α-androstan-3-one p-<N,N-bis(2-chloroethyl)amino>phenylbutyrate ester
    4-(3-carboxypropyl)-N,N-bis(2-chloroethyl)benzeneamine oxide

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