Добро пожаловать в GlobalChemMall

ВСЕ КАТЕГОРИИ
Categories
Изображение chenodeoxycholic acid

chenodeoxycholic acid

Получить последние цены >

Цена FOB $1.00

начало: Китай

Кас Но: 474-25-9

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 100 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

Поставщик:

Условия платежа:

немедленный запрос

* Пожалуйста, запросите у нас котировки

Добавить в список пожеланий

* Назовите свою цену
* Начать заказывать не значит покупать сейчас

  • Характеристики продукции
  • Описание продукта
  • Quick Details

    CAS No.:
    474-25-9
    Other Names:
    Chenodeoxycholic acid
    MF:
    C24H40O4
    EINECS No.:
    207-481-8
    Place of Origin:
    Shanghai, China
    Type:
    Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Antineoplastic Agents, Cardiovascular Agents, Central Nervous System Agents, Gastrointestinal Agents
    Grade Standard:
    Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade
    Brand Name:
    Terppon
    Model Number:
    1
    Purity:
    99%
    color:
    white

    Packaging&Delivery

    Packaging Details
    in 25kg drum
    Port
    shanghai
    Lead Time:
    1 week
  • Property

    CAS No.: 474-25-9 Formula: C24H40O4 Molecular Weight: 392.57200

    Description

    Chenodeoxycholic acid (also known as chenodesoxycholic acid, chenocholic acid and 3α,7α-dihydroxy-5β-cholan-24-oic acid) is a bile acid. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167°C. Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids produced by the liver.
    It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name (Greek: χήν = goose).
    Chenodeoxycholic acid and cholic acid are the two primary bile acids in humans. Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid.
    Chenodeoxycholic acid is synthesized in the liver from cholesterol by a process which involves several enzymatic steps. Like other bile acids, it can be conjugated in the liver with taurine or glycine, forming taurochenodeoxycholate or glycochenodeoxycholate. Conjugation results in a lower pKa. This means the conjugated bile acids are ionized at the usual pH in the intestine and will stay in the gastrointestinal tract until reaching the ileum where most will be reabsorbed. Bile acids form micelles which facilitate lipid digestion. After absorption, they are taken up by the liver and resecreted, so undergoing an enterohepatic circulation. Unabsorbed chenodeoxycholic acid can be metabolised by bacteria in the colon to form the secondary bile acid known as lithocholic acid.
    Choendeoxycholic acid is the most potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR). The transcription of many genes is activated by FXR.

    Basic Info

    Chemical Name chenodeoxycholic acid
    Synonyms

    CDCA;
    Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7α)-;
    3α,7α-Dihydroxy-5β-cholanic Acid;
    Chenodeoxycholic Acid;
    Chendiol;
    Fluibil;
    Chenodex;
    Chenix;
    Hekbilin;
    anthropododesoxycholicacid;
    chendol;
    Kebilis;
    Ulmenide;
    Chenocol;
    5β-Cholanic Acid-3α,7α-diol;

    CAS No. 474-25-9
    Molecular Formula C24H40O4
    Molecular Weight 392.57200
    PSA 77.76000
    LogP 4.47790

    Properties

    Appearance & Physical State white to off-white crystalline powder
    Density 1.128g/cm3
    Boiling Point 547.1ºC at 760 mmHg
    Melting Point 167-171ºC
    Flash Point 298.8ºC
    Refractive Index 1.558
    Water Solubility PRACTICALLY INSOLUBLE
    Storage Condition Store in a cool, dry place. Store in a tightly closed container.

    Safety Info

    RTECS FZ1980000
    Safety Statements S36/37-S45
    HS Code 2918990090
    WGK Germany 2
    Risk Statements R63
    Hazard Codes Xn

    Synthesis Route

    lithocholic acidDeoxycholic Acid+chenodeoxycholic acid
    Ethanol+3,7-DIKETO-5BETA-CHOLAN-24-OIC ACIDchenodeoxycholic acid+7-oxolithocholic acid
    3α,7α-dihydroxy-12-oxo-5β-cholanic acidchenodeoxycholic acid

    Precursor

    3α,7α-dihydroxy-12-oxo-5β-cholanic acid
    methyl (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-diacetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
    CHENODEOXYCHOLIC ACID SODIUM
    Methyl 3-α,7-α-diacetoxy-12-oxo-5-β-cholan-24-oate

    Downstream Product

    7α-hydroxycholest-4-en-3-one
    7-oxolithocholic acid
    METHYL CHENODEOXYCHOLATE
    ursodeoxycholic acid

Популярные теги: chenodeoxycholic acid, Китай, производитель, поставщик, фабрика, оптовая торговля, низкая цена, высокое качество