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ceftaroline fosamil acetate

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Origin: China

Cas No: 400827-46-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 400827-46-5 Formula: C22H21N8O8PS4 Molecular Weight: 684.68500

Description

Ceftaroline fosamil (INN) , brand name Teflaro in the US and Zinforo in Europe, is an advanced-generation cephalosporin antibiotic. It is active against methicillin-resistant Staphylococcus aureus (MRSA) and Gram-positive bacteria. It retains the activity of later-generation cephalosporins having broad-spectrum activity against Gram-negative bacteria. It is currently being investigated for community-acquired pneumonia and complicated skin and skin structure infection.
Ceftaroline is being developed by Forest Laboratories, under a license from Takeda. Ceftaroline has received approval from the U.S. Food and Drug Administration for the treatment of community-acquired bacterial pneumonia and acute bacterial skin infections on October 29, 2010. In vitro studies show it has a similar spectrum to ceftobiprole, the only other fifth-generation cephalosporin to date, although no head-to-head clinical trials have been conducted. Ceftaroline and ceftobiprole are on an unnamed subclass of cephalosporins by the Clinical and Laboratory Standards Institute (CLSI).

Basic Info

Chemical Name	ceftaroline fosamil acetate
Synonyms	Teflaro; (6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,acetate; Ceftaroline fosamil; PPI 0903; Ceftaroline fosamil acetate anhydrous; UNII-EZ9W6O5S09; Zinforo; Ceftaroline fosamil acetate;
CAS No.	400827-46-5
Molecular Formula	C22H21N8O8PS4
Molecular Weight	684.68500
PSA	346.85000
LogP	1.85800