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Cefpirome

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Origin: China

Cas No: 84957-29-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 84957-29-9 Formula: C22H22N6O5S2 Molecular Weight: 514.57700

Description

Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, and Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria.

Basic Info

Chemical Name	Cefpirome
Synonyms	HR-810; Keitim; Cefpiroma; Cefpiromum; CEFPIROME SULPHATE;
CAS No.	84957-29-9
Molecular Formula	C22H22N6O5S2
Molecular Weight	514.57700
PSA	207.46000
LogP	-0.13390

Properties

Appearance & Physical State	White or almost white crystalline powder

Safety Info

Safety Statements	S22-S26-S36/37/39
HS Code	3003201900
Risk Statements	R36/37/38; R42/43
Hazard Codes	Xi

Synthesis Route

cefotaxime→Cefpirome
cefotaxime+2,3-Cyclopentenopyridine→Cefpirome
trimethylsilyl (6R,7R)-3-(acetoxymethyl)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate→Cefpirome

Precursor

(6R,7R)-3-((6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-yl)methyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
trimethylsilyl (6R,7R)-3-(acetoxymethyl)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
cefotaxime
p-methoxybenzyl 7-phenylacetamido-3-(2,3-cyclopenteno-1-pyridinio)-3-cephem-4-carboxylate iodide

Downstream Product

cefpirome
(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-N-(2-oxoethyl)acetamide
Cefpirome Sulfate

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