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Cbz-L-tert-Leucine

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Origin: China

Cas No: 62965-10-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 62965-10-0 Formula: C14H19NO4 Molecular Weight: 265.30500

    Description

    Leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors.

    Basic Info

    Chemical Name Cbz-L-tert-Leucine
    Synonyms

    3-Methyl-N-[(phenylmethoxy)carbonyl]-L-valine;
    Z-TLE-OH;
    (2S)-3,3-Dimethyl-2-[(phenylmethoxy)carbonyl]aminobutyric acid;
    N-Carbobenzoxy-(S)-tert-leucine;
    Z-(TBU)GLY-OH;
    Z-L-TERT-LEUCINE;
    N-benzyloxycarbonyl-3-methyl-L-valine;
    CBZL-L-TERT-LEUCINE;
    N-Benzyloxycarbonyl-tert-leucine;
    Z-L-T-BUTYLGLYCINE;
    (S)-2-(((benzyloxy)carbonyl)amino)-3,3-dimethylbutanoic acid;
    Cbz-N-tert-butylglycine;
    Benzyloxycarbonyl-L-tert-leucine;
    2(S)-<<(benzyloxy)carbonyl>amino>-3,3-dimethylbutanoic acid;
    (S)-2-(Benzyloxycarbonylamino)-3,3-dimethylbutanoic acid;
    N-Benzyloxycarbonyl-L-tert-leucine;

    CAS No. 62965-10-0
    Molecular Formula C14H19NO4
    Molecular Weight 265.30500
    PSA 75.63000
    LogP 2.80300

    Properties

    Appearance & Physical State White powder
    Density 1.16 g/cm3
    Boiling Point 436.4ºC at 760 mmHg
    Flash Point 217.7ºC
    Refractive Index 1.528
    Storage Condition Refrigerator

    Safety Info

    HS Code 2924299090

    Synthesis Route

    N-(Benzyloxycarbonyloxy)succinimide+L-tert-LeucineCbz-L-tert-Leucine
    N-cyclohexylcyclohexanamine,(2S)-3,3-dimethyl-2-(phenylmethoxycarbonylamino)butanoic acidCbz-L-tert-Leucine
    L-tert-Leucine+Benzyl chloroformateCbz-L-tert-Leucine

    Precursor

    Benzyl chloroformate
    N-(Benzyloxycarbonyloxy)succinimide
    L-tert-leucinamide
    L-tert-Leucine

    Downstream Product

    Methyl (2S)-2-amino-3,3-dimethylbutanoate
    L-tert-Leucine

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