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budesonide

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Origin: China

Cas No: 51333-22-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    51333-22-3
    Other Names:
    Budesonide
    MF:
    C25H34O6
    EINECS No.:
    257-139-7
    Place of Origin:
    Shanghai, China
    Type:
    Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Antineoplastic Agents, Antipyretic Analgesics and NSAIDs, Auxiliaries and Other Medicinal Chemicals, Blood System Agents, Electrolyte Balance and Dialysis Agents, Endocrine System Agents
    Grade Standard:
    Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade
    Brand Name:
    Terppon
    Model Number:
    822
    Purity:
    99%
    color:
    white

    Packaging&Delivery

    Packaging Details
    in 25kg drum
    Port
    SHANGHAI
    Lead Time:
    1 week
  • Property

    CAS No.: 51333-22-3 Formula: C25H34O6 Molecular Weight: 430.53400

    Description

    Budesonide (BUD), sold under the brand name Pulmicort among others, is a steroid medication. It is available as an inhaler, pill, and nasal spray. The inhaled form is used in the long term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis and microscopic colitis.
    Common side effects with the inhaled form include respiratory infections, cough, and headaches. Common side effects with the pills include feeling tired, vomiting, and joint pains. Serious side effects include an increased risk of infection, loss of bone strength, and cataracts. Long term use of the pill form may cause adrenal insufficiency. Stopping the pills suddenly following long term use may therefore be dangerous. The inhaled form is generally safe in pregnancy. Budesonide is mainly a glucocorticoid.
    Budesonide was initially patented in 1973. Commercial use as an asthma medication began in 1981. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. Some forms are available as a generic medication. The wholesale price in the developing world for an inhaler containing 200 doses is about 5 to 7 USD as of 2014. As of 2015 the cost for a typical month of medication in the United States is 100 to 200 USD.

    Basic Info

    Chemical Name budesonide
    Synonyms

    Respules;
    Budesonide;
    Budesonide,(11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione;
    S-1320;
    Entocort;
    SPIROCORT;
    16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione;
    Budeson;
    Micronyl;
    BIDIEN;
    PULMICORT;
    RHINOCORT;
    PREFERID;

    CAS No. 51333-22-3
    Molecular Formula C25H34O6
    Molecular Weight 430.53400
    PSA 93.06000
    LogP 2.71680

    Properties

    Appearance & Physical State white solid
    Density 1.27 g/cm3
    Boiling Point 599.7ºC at 760mmHg
    Melting Point 221-232ºC (dec.)
    Flash Point 201.8ºC
    Refractive Index 1.592
    Stability Stable at normal temperatures and pressures.
    Storage Condition Store at RT

    Safety Info

    RTECS TU3723000
    Safety Statements S22-S36
    HS Code 29372900
    WGK Germany 3
    Risk Statements R40
    Hazard Codes Xn

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Inhalation TCLo - Lowest published toxic concentration Human - man 34 ug/kg 1.Skin and Appendages-dermatitis, allergic (after systemic exposure)
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat >3200 mg/kg 1.Nutritional and Gross Metabolic-weight loss or decreased weight gain
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 138 mg/kg 1.Behavioral-altered sleep time (including change in righting reflex)
    2.Blood-changes in spleen

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