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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> BRL-32872
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BRL-32872

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Origin: China

Cas No: 113241-09-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 113241-09-1 Formula: C29H35N3O7 Molecular Weight: 537.60400

    Description

    BRL-32872 is an experimental drug candidate that provides a novel approach to the treatment of cardiac arrhythmia. Being a derivative of verapamil, it possesses the ability to inhibit Ca+2 membrane channels. Specific modifications in hydrogen bonding activity, nitrogen lone pair availability, and molecular flexibility allow BRL-32872 to inhibit K+ channels as well. As such, BRL-32872 is classified as both a class III (K+ blocking) and class IV (Ca+2 blocking) antiarrhythmic agent.

    Basic Info

    Chemical Name BRL-32872
    Synonyms

    (N-(3,4-dimethoxyphenyl)-N-3-(N'-2-(3,4-dimethoxyphenyl)-ethyl-N'-methyl-amino)-propyl)-N'-4-nitrobenzamide hydrochloride;
    N-(3,4-Dimethoxy-phenyl)-N-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino}-propyl)-4-nitro-benzamide;

    CAS No. 113241-09-1
    Molecular Formula C29H35N3O7
    Molecular Weight 537.60400
    PSA 106.29000
    LogP 5.36380

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