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azithromycin

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Origin: China

Cas No: 83905-01-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 83905-01-5 Formula: C38H72N2O12 Molecular Weight: 748.98400

    Description

    Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, strep throat, pneumonia, traveler's diarrhea, and certain other intestinal infections. It may also be used for a number of sexually transmitted infections including chlamydia and gonorrhea infections. Along with other medications, it may also be used for malaria. It can be taken by mouth or intravenously with doses once per day.
    Common side effects include nausea, vomiting, diarrhea and upset stomach. An allergic reaction or a type of diarrhea caused by Clostridium difficile is possible. No harm has been found with use during pregnancy. Its safety during breastfeeding is not confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thus stopping bacterial growth.
    Azithromycin was first made in 1980. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic medication and is sold under many trade names worldwide. The wholesale cost in the developing world is about 0.18 to 2.98 USD per dose. In the United States it is about 33 USD for a course of treatment.

    Basic Info

    Chemical Name azithromycin
    Synonyms

    Aziwok;
    Azimin;
    xz405;
    Azenil;
    Aztrin;
    XZ-450;
    Azithromycin;
    Setron;
    Zifin;
    Tobil;
    Zeto;

    CAS No. 83905-01-5
    Molecular Formula C38H72N2O12
    Molecular Weight 748.98400
    PSA 180.08000
    LogP 1.83860

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.18 g/cm3
    Boiling Point 822.1ºC at 760 mmHg
    Melting Point 113-115ºC
    Flash Point 451ºC
    Refractive Index 1.536
    Stability Stable. Incompatible with strong oxidizing agents.
    Storage Condition Store at -20ºC

    Safety Info

    RTECS RN6960000
    HS Code 2941500000
    Hazard Codes Xi

    Synthesis Route

    Formaldehyde+(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-oneazithromycin
    azithromycin
    Formaldehydeazithromycin

    Precursor


    formic acid
    Formaldehyde
    (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one

    Downstream Product

    (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,13-tetrahydro xy-3,5,6,8,10,12,14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadecan -11-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
    (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-11-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
    3'-N,N-Di(desmethyl) Azithromycin
    L-cladinose

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