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AND017

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Origin: China

Cas No: 159325-45-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 159325-45-8 Formula: C23H35NO2 Molecular Weight: 357.53000

    Description

    (2α,3α,5α,16β)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-one is an impuritiy of Rocuronium bromide, an aminosteroid and a competitive neuromuscular blocker.

    Basic Info

    Chemical Name AND017
    Synonyms

    CAS No. 159325-45-8
    Molecular Formula C23H35NO2
    Molecular Weight 357.53000
    PSA 32.84000
    LogP 3.98770

    Synthesis Route

    2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one→AND017
    pyrrolidine→AND017
    pyrrolidine→AND017+2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one

    Precursor

    pyrrolidine
    Acetic anhydride
    (2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol
    2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one

    Downstream Product

    (2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol
    (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol

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