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all-trans-4-hydroxyretinoic acid

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Origin: China

Cas No: 66592-72-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 66592-72-1 Formula: C20H28O3 Molecular Weight: 316.43500

Description

A metabolite of all-trans Retinoic acid.

Basic Info

Chemical Name	all-trans-4-hydroxyretinoic acid
Synonyms	rac all-trans 4-Hydroxy Retinoic Acid;
CAS No.	66592-72-1
Molecular Formula	C20H28O3
Molecular Weight	316.43500
PSA	57.53000
LogP	4.57340

Properties

Density	1.075g/cm3
Boiling Point	506.5ºC at 760 mmHg
Flash Point	274.2ºC
Refractive Index	1.574

Synthesis Route

all-trans-retinoic acid→all-trans-4-oxoretinoic acid+all-trans-4-hydroxyretinoic acid
rac-(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-hydroxy-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid ethyl ester→all-trans-4-oxoretinoic acid+all-trans-4-hydroxyretinoic acid
ethyl (2E,4E,6E,8E)-9-(3-acetoxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoate→all-trans-4-hydroxyretinoic acid

Precursor

ethyl (2E,4E,6E,8E)-9-(3-acetoxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoate
ethyl (2E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
all-trans-4-oxoretinoic acid
all-trans-retinoic acid

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