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algestone acetonide

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Origin: China

Cas No: 4968-09-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 4968-09-6 Formula: C24H34O4 Molecular Weight: 386.52400

Description

Algestone acetonide (USAN, BAN) (developmental code name W-3395), also known as algestone 16α,17α-acetonide or 16α,17α-isopropylidenedioxyprogesterone, is a steroidal progestin and glucocorticoid anti-inflammatory that was never marketed. It is the acetonide ester of algestone.

Basic Info

Chemical Name	algestone acetonide
Synonyms	16a,17a-isopropylidenedioxyprogesterone; 4-PREGNEN-16ALPHA,17ALPHA-DIOL-3,20-DIONE 16,17-ACETONIDE; progesterone 16,17-acetonide; Alphasone acetonide; ALGESTONE ACETONIDE;
CAS No.	4968-09-6
Molecular Formula	C24H34O4
Molecular Weight	386.52400
PSA	52.60000
LogP	4.60750

Properties

Density	1.16g/cm3
Boiling Point	501.5ºC at 760 mmHg
Flash Point	216.1ºC
Refractive Index	1.554

Synthesis Route

3β-acetoxy-16α,17α-isopropylidenedioxypregn-5-ene-20-one→algestone acetonide
3β,-hydroxy-16α,17α-isopropylidenedioxy-5α-pregn-20-one→algestone acetonide+pregn-4-ene-9α,16α,17α-triol-3,20-dione 16,17-acetonide

Precursor

3β,-hydroxy-16α,17α-isopropylidenedioxy-5α-pregn-20-one
3β-acetoxy-16α,17α-isopropylidenedioxypregn-5-ene-20-one

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