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alfacalcidol

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Origin: China

Cas No: 41294-56-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
41294-56-8
Other Names:
1-hydroxycholecalciferol
MF:
C27H44O2
EINECS No.:
N/M
Place of Origin:
Zhejiang, China
Type:
Vitamins, Amino Acids and Coenzymes
Grade Standard:
Medicine Grade
Brand Name:
Crene
Model Number:
cas 41294-56-8
Purity:
98% min
Exact Mass:
400.334
Molecular Weight:
400.637
PSA:
40.46
LogP:
6.5898
Target:
VD/VDR
Pathway:
Vitamin D Related
Solubility:
DMSO : ≥ 50 mg/mL (124.80 mM)
Packaging&Delivery
Packaging Details
Packaging according to customer requirements.
Port
shanghai
Lead Time:
Quantity(Grams) 1 - 30 >30
Est. Time(days) 3 To be negotiated

Property

CAS No.: 41294-56-8 Formula: C27H44O2 Molecular Weight: 400.63700

Description

Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.
Alfacalcidol has a weaker impact on calcium metabolism and parathyroid hormone levels than calcitriol, however alfacalcidol has significant effects on the immune system, including regulatory T cells. It is considered to be a more useful form of vitamin D supplementation, mostly due to much longer half-life and lower kidney load. It is the most commonly prescribed vitamin D metabolite for patients with end stage renal disease, given that impaired renal function alters the ability to carry out the second hydroxylation step required for the formation of the physiologically active form of vitamin D, 1,25-dihydroxyvitamin D3. Alfacalcidol is an active vitamin D3 metabolite, and therefore does not require the second hydroxylation step in the kidney.
Used as a poultry feed additive, it prevents tibial dyschondroplasia and increases phytate bioavailability.[original research?]

Basic Info

Chemical Name	alfacalcidol
Synonyms	Bondiol; Alpharol; unalpha; Un Alfa; Etalpha; oxydevit; 1a-Hydroxyvitamin D3; alfarol; Alfacalcidol;
CAS No.	41294-56-8
Molecular Formula	C27H44O2
Molecular Weight	400.63700
PSA	40.46000
LogP	6.58980

Properties

Appearance & Physical State	white to off-white crystalline powder
Density	1.01 g/cm3
Boiling Point	531.5ºC at 760 mmHg
Melting Point	136ºC
Flash Point	222.6ºC
Refractive Index	1.534
Stability	Stable at normal temperatures and pressures.
Storage Condition	-20ºC

Safety Info

RTECS	VS2851000
Hazard Class	6.1(a)
Safety Statements	28-36/37-45-36-26
HS Code	29361000
Packing Group	I
WGK Germany	3
RIDADR	UN 2811 6.1/PG 1
Risk Statements	R26/27/28
Hazard Codes	T+; Xi
Symbol	GHS06
Caution Statement	P260; P264; P280; P284; P301 + P310; P302 + P350
Hazard Declaration	H300 + H310 + H330
Signal Word	Danger