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alclometasone dipropionate

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Origin: China

Cas No: 66734-13-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 66734-13-2 Formula: C28H37ClO7 Molecular Weight: 521.04200

    Description

    Alclometasone-17,21-dipropionate is an synthetic glucocorticoid steroid used for inflammatory skin conditions. Alclometasone-17,21-dipropionate is topically used in dermatology as an anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.

    Basic Info

    Chemical Name alclometasone dipropionate
    Synonyms

    Almeta;
    ALCLOMETASONEDIPROPIONATE,USP;
    Delonal;
    alclovate;
    Alclometasone-17,21-dipropionate;
    Ddlonal;
    Aclovate;
    alclometasone Dipropionate;
    Modrasone;
    Aclosone;
    Vitra;

    CAS No. 66734-13-2
    Molecular Formula C28H37ClO7
    Molecular Weight 521.04200
    PSA 106.97000
    LogP 3.94270

    Properties

    Density 1.26g/cm3
    Boiling Point 636ºC at 760 mmHg
    Flash Point 338.4ºC
    Refractive Index 1.562

    Safety Info

    Caution Statement P280
    Signal Word Warning
    Hazard Declaration H361d
    Symbol GHS08

    Synthesis Route

    16α-methyl-11β,17α,21-trihydroxy-1,4,6-pregnatriene-3,20-dione 17,21-dipropionate→alclometasone dipropionate
    16α-Methyl Prednisolone 21-Acetate→alclometasone dipropionate
    16α-methyl-11β,17α,21-trihydroxy-1,4,6-pregnatriene-3,20-dione→alclometasone dipropionate

    Precursor

    16α-methyl-11β,17α,21-trihydroxy-1,4,6-pregnatriene-3,20-dione 21-acetate
    16α-Methyl Prednisolone 21-Acetate
    16α-methyl-11β,17α,21-trihydroxy-1,4,6-pregnatriene-3,20-dione
    16α-methyl-11β,17α,21-trihydroxy-1,4,6-pregnatriene-3,20-dione 17,21-dipropionate

    Downstream Product

    alclometasone

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