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alamifovir

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Origin: China

Cas No: 193681-12-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 193681-12-8 Formula: C19H20F6N5O5PS Molecular Weight: 575.42200

    Basic Info

    Chemical Name alamifovir
    Synonyms

    MCC 478;

    CAS No. 193681-12-8
    Molecular Formula C19H20F6N5O5PS
    Molecular Weight 575.42200
    PSA 158.72000
    LogP 5.47450

    Properties

    Density 1.61g/cm3
    Boiling Point 635.9ºC at 760mmHg
    Flash Point 338.4ºC
    Refractive Index 1.582
    Vapor Pressure 4.51E-16mmHg at 25°C

    Synthesis Route

    4-METHOXYBENZENETHIOL+2-amino-6-chloro-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester→alamifovir
    bis(2,2,2-trifluoroethyl) [(2-chloroethoxy)methyl]phosphonate→alamifovir
    1,1,1-trifluoro-2-[2-iodoethoxymethyl(2,2,2-trifluoroethoxy)phosphoryl]oxyethane→alamifovir

    Precursor

    bis(2,2,2-trifluoroethyl) [(2-chloroethoxy)methyl]phosphonate
    4-Mercaptophenol
    1,1,1-trifluoro-2-[2-iodoethoxymethyl(2,2,2-trifluoroethoxy)phosphoryl]oxyethane
    2-amino-6-chloro-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester

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